Pros
Very bright people work here. There is a lot of knowledge to gained from colleagues. Take advantage of it. For a relatively small research institute they have incredible shared facilities. Whatever kind of experiment you want to do, you can probably do here. There is a ton of experiment support for researchers. Admin and facility service are there to facilitate the researchers. Labs run as smoothly as your PI can manage things.
Cons
It's an academic research institute so a lot of cons just come with that territory. Pay is low and turnover is high. Most staff outside the faculty are only here temporarily: technicians, grad students, post-docs, etc. Your manager will be your PI. If you have a bad PI then you'll have a bad time. Wistar, and every other academic research organization on Earth has a hard time dealing with toxic faculty. As long as they bring in grant money and publish in big journals they will be slow to take any action against them. You just have to avoid working in these labs unless you have a lot of patience and very thick skin.