Bioinformatics Software Engineer Interview Questions


Bioinformatics Software Engineer interview questions shared by candidates

Top Interview Questions

Sort: Relevance|Popular|Date
Bioinformatics Developer was asked...28 November 2018

What kinds of programming languages do I usually code in? Which one do I feel the most comfortable with?

1 Answers

It depends on the purpose of the project. I use R for data analytics and Python and Perl for development. Less

Public Health Agency of Canada

What do you know about Markov chains?

1 Answers

Markov chains, or HMM, is a statistical random model for predicting future status. It is widely used in bioinformatics, genome annotation, voice recognition and weather forecast. It estimates the probability of next status based on the current available datasets. Less

Columbia University

How many exomes do you sequence a week?

1 Answers

Uhhhhhh I work in the core. It varies.


What are ways to reduce unwanted errors in production?

1 Answers

I suggested code testing and code coverage. They did not like this. The answer they wanted was; a statistical analysis of the results to show that the differences were 'good enough' and therefore justified updating the code. Less

Public Health Agency of Canada

What do you know about the BLAST algorithm?

1 Answers

BLAST is a sequence searching tool using query sequence(s) to find similar sequences in a database(subject). It uses statistics to give the matched sequences a number of parameters such as similarity, score, e-value, gap number. It is applied in bioinformatics to get homologous sequences. Less


Explain how you would teach a computer to navigate a plaza.

1 Answers

Gather data, and perform ML. The interviewer was looking for a high-level approach to the question. Instead of path-planning, etc. they wanted "gather data." Less


Why don't you code in Python like we do?

1 Answers

Because I am a dinosaur.


What tools would you use to perform variant analysis (finding SNPs, etc.)?

Memorial Sloan Kettering Cancer Center

How do you evaluate the success of an ML model beyond the accuracy score?


Leetcode/Google/Microsoft style software engineering questions

Viewing 1 - 10 of 25 interview questions

See Interview Questions for Similar Jobs

Glassdoor has 25 interview questions and reports from Bioinformatics software engineer interviews. Prepare for your interview. Get hired. Love your job.