Working 60+ hour weeks is normal here, engineers also work weekends frequently. It's hard to get leave for more than a week (even though it's supposed to be unlimited). There's a culture of sexism and sexist jokes which seems to be tolerated by senior engineers and management.
Lots of engineering problems - system failures, downtime, lots of on-call work and stress, cost cutting is pretty rampant too, it's hard to get the things you need to do your job and you have to work with limited resources.
The pay is also much lower than you can get at other companies. If you want high stress, low compensation then Uber is the place for you.